The Acidophilus Story

Beneficial bacteria make good foods better

Long before it became possible to see bacteria with the aid of microscopes, people used these minute organisms to produce cultured dairy products such as cheese, sour cream, and yogurt. Fermented milks have been safely consumed throughout the world for thousands of years, as evidenced by their depiction in Sumerian wall paintings dating back to 2500 B.C. and their mention in the Old Testament (Genesis 18:8). Yoghurt consumption is part of the folklore of many long-lived populations, including the Ural Mountain people, many of whom live more than 100 years! Widely recognized as an important part of a healthy diet, cultured dairy products have grown in popularity, with more cultured dairy foods available today than ever before.

Food sources of lactobacilli* from around the world

Cultured Dairy Products Beneficial Bacteria
Yogurt Streptococcus thermophilus
Lactobacillus bulgaricus
Lactobacillus acidophilus
Buttermilk Lactobacillus lactis
Streptococcus cremoris
Sour cream Streptococcus cremoris
Kefir Lactobacillus acidophilus
Lactobacillus caucasicus
Cheeses Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus caucasicus
Lactobacillus helveticus
Lactobacillus lactis
Lactobacillus plantarum
Streptococcus cremoris
Streptococcus faecium
Cottage cheese Lactobacillus lactis
Streptococcus cremoris
Acidophilus milk Lactobacillus acidophilus
Bulgaricus milk Lactobacillus bulgaricus
Yakult Lactobacillus casei
Bifidus milk Bifidobacterium bifidum
Bifidobacterium longum

* Bacteria that produce lactic acid as an end product of milk fermentation.

The birth of probiotics

Most people are familiar with antibiotics, which physicians prescribe to combat strains of bacteria which cause disease. In contrast, other strains of bacteria promote health and are called probiotics, from the Greek meaning “for life.” Probiotics are live microbial supplements which beneficially affect the host by improving its intestinal balance. Although anecdotal health claims for the regular consumption of cultured dairy products have circulated for centuries, only in this century have scientists begun to understand how these foods support health.

In 1908, Nobel Prize-winning scientist Elie Metchnikoff of the Pasteur Institute in Paris provided the first evidence that microorganisms may be responsible for the health-promoting effects of fermented milks. After observing that Bulgarian peasants lived to ripe, old ages, Metchnikoff became convinced that their health and longevity were linked to microbes in the soured milk they copiously drank. In his book The Prolongation of Life, he suggested that disease-causing (“bad”) bacteria could be eliminated by ingesting large amounts of Bulgarian sour milk, which contained a beneficial (“good”) bacterium later identified as Lactobacillus bulgaricus. These organisms were part of a group called Lactobacilli, or bacteria that produce lactic acid as an end product of milk fermentation.

Lactic acid-producing bacteria tip the scales towards health

The human gastrointestinal tract is a diverse and complex ecosystem harbouring more than 400 species of bacteria. Their importance is demonstrated by their impressive presence: The large intestine alone contains about 1.5 kilograms of bacteria! This quantity of bacteria is not surprising given the tremendous effect of bacterial growth and metabolism on human health.

Not all bacteria are created or act equally, however. Some benefit the body and are required for optimal health, whereas others harm the body by producing toxins and even carcinogens. Those producing lactic acid promote health. By turning lactose (milk sugar) into lactic acid, they lower the pH of the colon and inhibit the growth of harmful bacteria. When lactic acid-producing bacteria are in short supply, undesirable bacteria can increase in number. The results can range from simple digestive discomfort to more serious gastrointestinal disease. Imbalance - a scarcity of “good” bacteria or a surplus of “bad” bacteria - can set the stage for a cascade of events that may ultimately trigger disease.

Examples of lactic-acid producing (“good”) bacteria

Bifidobacterium bifidum
Lactobacillus acidophilus
Lactobacillus casei
Lactobacillus bulgaricus
Streptococcus thermophilus

Did you know…some good bacteria have names that sound like bad bacteria? Streptococcus, for instance, can be a beneficial bacterium, although most people think of strep throat when they hear the word. Streptococcus refers only to the shape of the bacterium, and has nothing to do with its ability to promote health or cause disease. (Strept means “twisted” and coccus means “round.”) Streptococcus thermophilus, Streptococcus cremoris, and Streptococcus faecium have been safely used for centuries to produce cultured dairy products.

Examples of potentially pathogenic (“bad”) bacteria

Clostridium botulinum
Escherichia coli
Salmonella typhimurium
Shigella dysenteriae

Normally, there is a balance among the various bacteria inhabiting the intestine. However, with the onset of disease or the use of antibiotics, this balance is upset and the Lactobacilli are among the first to become depleted.

How beneficial bacteria promote health

Lactic acid-producing bacteria tend to healthfully combine with toxins (which may include cholesterol, heavy metals, and carcinogens) and bile acids. While this action prevents toxic products from being reabsorbed, it kills the microorganisms, which are then eliminated from the body as solid waste. This mechanism may help explain the increased longevity of people who regularly consume cultured dairy foods.

Lactobacillus acidophilus (“acid-loving, lactic acid-producing bacterium”), the most well-known bacterial hero, first gained attention as a dietary supplement in the 1920s. In 1935 the first results of clinical trials were published that showed that acidophilus normalised bowel function in patients with chronic constipation.

Since then, scientists have identified many other health benefits of lactic acid-producing bacteria, presumably resulting indirectly from their ability to:

  • produce lactic acid, thereby increasing the acidity of the intestines and inhibiting bacterial villains such as Clostridium, Salmonella, Shigella, and E. coli.
  • decrease the production of a variety of toxic or carcinogenic metabolites. For instance, Lactobacillus acidophilus can suppress the formation of cancer-causing amines and cancer-promoting enzymes in the intestines of humans and animals.
  • aid absorption of minerals, especially calcium, due to increased intestinal acidity.
  • use lactose, to which many people are intolerant, to produce lactic acid. Because cultured milk products are much lower in lactose, they are better tolerated than milk alone. Additionally, Lactobacilli are capable of producing enzymes that break down lactose.
  • produce a wide range of antibiotic substances (acidophilin, bacteriocin, etc.) which help control the level of pathogenic bacteria and fungi such as Candida.
  • produce vitamins, especially B-vitamins and vitamin K.
  • act as barriers to prevent pathogenic bacteria from colonizing the intestines.

Each strain of beneficial bacteria is unique: Each produces special enzymes, detoxifies different substances, and colonizes distinct territories in the intestines. For this reason, a broad spectrum of organisms is desirable.

Good bacteria increase the resistance to disease. When resistance is low, the content of lactic acid bacteria in the intestines is considerably lower than usual. A compelling demonstration of this fact was an experiment in which only 10 bad bacteria (Salmonella) were necessary to kill a guinea pig with an inadequate amount of beneficial microflora, but about a trillion cells were required to kill an animal with its full natural beneficial bacteria present!

Health benefits of beneficial bacteria

Scientific literature documents the healthful effects of cultured dairy products and/or probiotic supplements in a number of conditions:

  • diarrhoea
  • constipation
  • colitis (inflamed colon)
  • gastroenteritis (inflamed stomach and intestines)
  • infections with pathogenic bacteria and fungi (e.g., yeast infections, infections causing food poisoning, etc.)
  • flatulence
  • lactose intolerance
  • impaired digestion
  • cancer, especially colon cancer
  • poor utilization of food nutrients

The probiotic gap

The following factors can deplete good bacteria and upset their balance in the intestines:

  • antibiotics, which can kill good as well as bad bacteria
  • other drugs
  • infections (bacterial, viral, and fungal)
  • diet (highly processed, low-fibre foods)
  • chronic diarrhoea
  • stress

The intestinal balance between good and bad bacteria in turn can affect:

  • nutritional status
  • efficacy of medications
  • physiological function
  • ageing
  • cancer
  • immune response
  • infection
  • comfort

It is often difficult to obtain beneficial bacteria in foods alone. And even if live bacteria are present, you’d have to eat a lot of yoghurt to consume enough bacteria to achieve an effect, especially considering the following:

  • Due to pasteurization, most popular brands of yoghurt do not contain live cultures.
  • Laboratory tests of various cultured milk products have shown that the bacterial strains that are supposed to be there often are not present or are present in very low levels.
  • Cooked foods do not contain live organisms. All cultured dairy products should be eaten raw to take advantage of any probiotic benefits.
  • Beneficial bacteria cannot survive the acidic environment of the stomach. Therefore few live organisms make it to the intestines to exert their beneficial effects.

Acidophilus plus supports a healthful balance!

Broad spectrum of organisms from the human food chain! Eating many types of cultured milk products from around the world on a daily basis would be an ideal - but impractical - way to consume diverse microorganisms. To provide broad-spectrum support for the health of the gastrointestinal tract, GNLD has selected and isolated only the best strains used to prepare whole foods: European yoghurt, acidophilus- fermented milk, bifidus-fermented milk, and Yakult, a popular Japanese fermented milk. The identity of all the strains is strictly and continuously controlled to insure that exactly the right strain is present every time. The product delivers five types of lactic acid-producing bacteria in a 1:1:1:1:1 ratio:

  • Lactobacillus acidophilus
  • Lactobacillus bulgaricus
  • Lactobacillus casei
  • Bifidobacterium bifidum
  • Streptococcus thermophilus

Convenient! Whereas dairy products are limited in their shelf-life, GNLD’s Acidophilus Plus has an extended shelf-life if stored as recommended (i.e., stored in a cool, dry place and refrigerated after opening). And while cultured dairy products can be inconvenient to transport, store, and sometimes, even locate, Acidophilus Plus is easy to take anywhere your busy lifestyle takes you! Taking just one capsule of Acidophilus Plus each day is a convenient way to help maintain a constant, healthful balance of intestinal flora.

Potency guaranteed! GNLD’s bacterial strains are cultivated under strict conditions to guarantee high levels of active bacteria - much higher numbers than are found in a serving of cultured dairy foods! In fact, one capsule of Acidophilus Plus contains as many beneficial bacteria as 10 one-cup servings of yoghurt or five 226.8g servings of acidophilus milk! Maintaining gastrointestinal health requires the presence of between 100 million and one billion bacteria per day. Each capsule of Acidophilus Plus is filled with five billion viable beneficial bacteria.

Targeted Delivery Technology! Our exclusive Targeted Delivery Technology protects the beneficial bacteria from the harsh, acidic environment of the stomach and maximizes the number of live bacteria that reaches the intestines. To produce Acidophilus Plus, diverse types of lactic acid-producing bacteria are specially processed together with gel-forming polysaccharides, which are insoluble in acidic conditions, and encapsulated in a hard-gelatin capsule. When the capsule encounters the acidic environment of the stomach, it dissolves, and the contents of the capsule form an insoluble matrix which protects the bacteria. When the stomach contents reach the intestines, the Gel-Guard matrix is dissolved, and the bacteria are released. The active cultures are delivered exactly where they must act to exert their healthful effects!